Category Archives: Y-chromosomes

Y-chromosome Validates the Bible

Foreword

Those who believe the Bible accept it by faith; however, there are many accounts in the Bible that are testable scientifically. One of these accounts is that of Noah having three sons and these three sons repopulated the entire earth after the flood . This paper provides scientific evidence that all men alive today came from one of three ancient ancestors. Our findings are based on Y-chromosome analysis. The analysis is simple, straightforward, and repeatable; anyone can understand it and repeat it. The data is fully documented herein and generated from mainstream scientific community sources (Reference 1 is the browser and Reference 2 contains the sequences used).

The Bible made the following proclamation thousands of years ago, and now we have the genetic tools to test its validity:

Genesis 9:19  These are the three sons of Noah: and of them was the whole earth overspread.

Genesis 10:32  These are the families of the sons of Noah, after their generations, in their nations: and by these were the nations divided in the earth after the flood. 

Background

We know that the Y-chromosome is passed from father to son, and, in general, each generation passes on a few genetic variants to the next generation. These variants provide genetic markers which are highly valuable for tracking ancestry. Geneticists sort people into groups called haplogroups because they contain like genetic markers. The haplogroups form a family tree for all humanity and allow us to trace ancestry back to our most ancient ancestors.

Former Work

We, at Genesis and Genetics, made a preliminary evaluation of Y-chromosome DNA genetic markers and discovered that all human men on earth came from one of three ancient ancestors (Reference 3). We found that any human man could trace his genetic markers back to one and only one of three ancient ancestors. Any man with a marker ‘A’ at rs9786139 is from one ancient ancestor, a marker ‘A’ at rs17306671 is from another ancient ancestor, and a marker ‘G’ at rs3900 is from the third ancient ancestor. It was easy to associate these three most ancient ancestors with Ham, Shem, and Japheth by looking at Biblical history of migration and nations. Ham had the ‘A’ at rs9786139; Shem had the ‘A’ at rs17306671; and Japheth had the ‘G’ at rs3900.

This former research was based on a study of 57 modern human men. All the men had one and only one of the three markers stated above.

Note: We use the terms “mutations,” “variants,” and “markers” interchangeably.

Confirmation

Since our original study, we have looked at many more sequences, a total of 1233 Y-chromosome genomes, and found they all conformed to our original findings.  Reference 4  documents the 1233 human genomes and which ones are from each of Noah’s three sons. All 1233 humans had one and only one of the three markers. There were no exceptions. This paper confirms our original findings and compares our Biblical ancestral family tree to that of mainline science.

Comparison to Mainline Science

In general, our analysis agreed with mainstream science concerning haplogroups. Therefore, our family tree uses the same haplogroups as our friends in mainstream science. But they are rooted differently. Here is the secular science tree followed by our family tree. There are several versions of the secular trees (called phylogenetic trees), but we, generally, used the one generated by the International Society of Genetic Genealogy, ISOGG (Reference 5).

 

Biblical Family tree

As one can see, the two trees are similar, but the root and flow of genetic markers are different. The secular tree is rooted in haplogroup A, and the Biblical tree is rooted in Noah dividing into three separate haplogroups; one from Ham; one from Shem; and one from Japheth. We do not present Noah’s DNA, but it is simply his three sons’ DNA less their genetic markers.

Finding the Tree Root

Armed with these 1233 diverse genomes, we began our search by noticing that a few mutations/genetic markers, were common in the population;  some were up to 52 percent of the population. It is quite logical to assume that the higher the mutation’s frequency, the better chance that it is at or near the root of our family tree.

For example, if a mutation is in 1/2 of the population, it probably originated when the population was approximately 2 men. If a mutation is in 1/10th of the male population, it probably originated when the male population was approximately 10. And if a mutation is in1/1,000,000), it probably originated when the world population was 1,000,000.

So, we decided that any mutation with a frequency of more than 5 percent could be one of Noah’s three sons. This assumption would allow for some genetic drift and the inability for our 1233 subjects to exactly match the whole world population distribution.

All Men came from three ancient ancestors

Next, we took each of the mutations with frequencies higher than 5 percent and used them to form genetic groups, i.e., haplogroups. Quickly, we realized that every mutation belonged to one and only one of three ancient ancestors.

It appeared that we found Shem, Ham, and Japheth. There was a Shem haplogroup, a Ham haplogroup, and a Japheth haplogroup. All 1233 genomes fit into one and only one of the three. There were no exceptions. The three root mutations had frequencies of 10%, 38%, and 52%. And, as expected, they added up to 100% of the population. Furthermore, Shem, Ham, and Japheth were associated with the three ancient ancestor mutations easily by looking at the geographical locations of each group and comparing them to Bible history. Ham went south and east; Japheth went north and east, and Shem populated the Near East and Europe.

Noah’s Y-chromosome is impossible to find directly. The reason is that he is the origin of all male humanity and he had, by definition, no genetic markers. Therefore, the way to find Noah’s Y-genome is by determining the genomes of his sons and deleting all their mutations.

The true root of humanity was Adam. Adam’s DNA went through the bottleneck of Noah. So we all came from Adam and we all came from Noah. Adam is the root of all humanity, and Noah is the root of post-flood humanity.

Genetic Mutations/Markers Flow in One Direction

Just as water flows downstream, so do genetic markers. Genetic markers flow from most ancient ancestors to modern ancestors. For instance, your great grandfather passed markers to your grandfather who passed additional markers to your father. Your father passed his additional markers to you,. And if you are a man, you too will pass new markers to your sons. Lineage flows downstream. More and more new markers appear in offspring as the generations pass. However, the original markers of your ancestors remain in your genome. A key point here is that as the markers flow away from the root, the new markers divide the offspring into sub-haplogroups. This dividing into sub-haplogroups shows the direction of the genetic marker flow.  Distant branches have only the markers close to the root, but are missing many of the markers in their cousins, second cousins etc.

Therefore, as expected, the data shows that markers flow from Noah’s three sons to their sub-haplogroups. Consider just haplogroup K, everyone from haplogroup K has the rs3900 G marker. Likewise, the sub-haplogroups have additional markers that show they are later generations forming smaller haplogroups such as M, N, O, P, Q, R, S, and T etc. T must come from K, but K cannot come from T.

Since genetic mutations/markers flow downstream, it is not possible that the root of the Y-chromosome family tree is rooted in a marker with a small frequency. In order for that to happen, it would take many bottlenecks, overwrites, drift, and other genetic contortions.

Full Population Representation

The three adjacent haplogroups, IJ, IJK, and K contain 100 percent (Ham 38%, Shem 10%, and Japheth 52%) of the 1233 genomes analyzed. In other words, they are the source of all modern humanity. Take any other combination of the other haplogroups and mix and match them, they do not represent all humanity; they do not add up to 100 percent. The only way you get one hundred percent is to use IJ, IJK, and K.

Biblical and Secular History

The haplogroups IJ, IJK, and K are comprised of people from Mid-East, West Asia, and Near East. According to the Biblical narrative, all humanity came from the Armenian mountains which which are in West Asia and close to the Near East and the Mid-East. In short, these haplogroups locations fit nicely into Biblical history.

The historical age began in Mesopotamia, shortly after the flood. These earliest writings document a worldwide flood and the world populated by the survivors of that flood. Nowhere do these legends and writings record mankind originating from any other part of the world.

Summary

The Y-chromosome DNA is the perfect vehicle for scientifically testing the portion of the Bible that says all modern human men were born of three ancient men. The Y-chromosome data of 1233 genomes corroborates the Biblical account. We now have a Biblical family tree and can trace our ancestry to the Biblical sons of Noah.

Future Work

We are in the process of identifying the DNA of Noah’s 16 grandsons in the family tree.

 

References:

  1. http://useast.ensembl.org/info/about/publications.html
  2. https://www.genome.gov/27528684/1000-genomes-project
  3. https://www.genesisandgenetics.org/2021/04/16/y-chromosome-migration-and-the-biblical-phylogenetic-tree-or-finding-ham-shem-and-japheth-via-y-chromosome/
  4. https://www.genesisandgenetics.org/Ancient.xlsx
  5. https://docs.google.com/spreadsheets/d/1Y0GXjhazYa46u0EpPA9b0Y0RVWuh5lDzww_o979mbjQ/edit#gid=1904113265
  6. https://useast.ensembl.org/index.html

 

 

Eve’s DNA

Eve’s DNA was perfect

Eve in the garden original art by HH 2021

The account of Eve is an interesting and important segment of our genetic history. The Bible says that God put Adam into a deep sleep, took one of Adam’s ribs, and made a woman (Genesis 2:21-22). Adam named her Eve and proclaimed that she was “bone of my bones and flesh of my flesh” (Genesis 2:23-24). Eve’s DNA, like Adam’s, was perfect. It was without mutations and immortal.

Eve’s DNA and science

So, how does modern science line up with this account? First of all, does the man’s rib contain enough genetic information to make a woman? The answer is “yes,” Adam’s ribs contained all the necessary genetic information to make Eve. However, it is interesting to note that if the first human were a woman, her rib would not contain enough information to make a man. This is because women do not have the y-chromosome. So, if the Bible stated that God created a woman first and then a man from her rib, the Bible would be in error; but, the Bible got it right and stands true. This all seems elementary to us now, but remember that the scriptures are much older than our knowledge of DNA.

Adam and Eve were near-identical twins

It follows, from both a Biblical and genetic perspective, that Eve was Adam’s feminine identical twin. When Adam said that Eve was “bone of my bones and flesh of my flesh” (Genesis 2:23-24), he was confirming this point. Is this possible? Can there be male/female identical twins? Yes, it is possible: if a geneticist takes two identical twin embryos and genetically engineers them so one has two X chromosomes and the other has one X and one Y chromosome, the resulting two humans will be identical male/female twins. Although rare, there are natural occurrences of male/female identical twins. For further information on this, just do an internet search on “male/female identical twins.”

Eve’s children

A common question to this notion of Adam and Eve being identical male/female twins is: “If Adam and Eve were identical twins, wouldn’t all their children also be identical to Adam and/or Eve?” The answer to this question is “No.” Adam and Eve were identical twins and they each had two copies of every gene. Due to a biological process called “meiosis,” these genes were shuffled differently for each of their children, and that fact coupled with epigenetic effects results in the chances of a child having identical DNA to Adam or Eve being infinitely small. This process of meiosis is easily understood, just search on “meiosis” and you will find many videos and detailed explanations.

Sin and mutations

When Adam and Eve ate the forbidden fruit, they sinned and reaped the penalty of sin. They became mortal and subject to genetic mutations. These mutations cause disease, deformities, and death, but they allow us to track our heritage. It is the consensus of both creation and secular scientists that all humans presently on earth come from one woman: “Eve” (creationists) and “Mitochondrial Eve” (secular scientists).

Genesis 3:20  And Adam called his wife’s name Eve; because she was the mother of all living.

Summary

In conclusion, Eve’s creation and genetic composition provide a fascinating bit of our human history that helps us understand our origins. It also demonstrates the convergence of modern science with the Biblical scriptures.

Here are some related articles if interested.

Adam’s DNA

Adam’s Rib

Genesis Chapter 1 and 2

 

Adam’s DNA

Adam’s DNA was perfect.

According to the Bible, God created Adam approximately 6000 years ago. His body was perfect and not destined to die; he was immortal. But we are not like Adam. We are mortal and subject to imperfections and disease. Why? The answer is simple: When sin entered the world our bodies began collecting DNA mutations. Fortunately, we hope someday to enjoy our original day-6 DNA: perfect and immortal.

Let’s look at what the Bible says:

Genesis 1:31  And God saw every thing that he had made, and, behold, it was very good. And the evening and the morning were the sixth day. 

Genesis 2:7  And the LORD God formed man of the dust of the ground, and breathed into his nostrils the breath of life, and man became a living soul. (KJV)

Science and Adam’s DNA

Adam became a living soul, the first living soul, which means Adam necessarily had all of the human genetic variations in his DNA. Everyone, including Eve, came from Adam’s DNA. Modern science has proclaimed that all Y-chromosomes came from one man. We call Him Adam, and secular science calls him Y-chromosome Adam. Modern science also declares that all humanity came from one woman. We call her Eve, and secular science calls her mitochondrial Eve; however, since Eve came from Adam, we all came from Adam. The point is that the Biblical version of human origins is scientifically in tune with the Bible.

(Note: If the Bible had proclaimed that the first human was a woman, the Bible would be in error, women do not have the y-chromosome.)

Humans have approximately 22,000 genes, and combinations of these genes give us variation in physical appearances, such as eye color, nose shape, foot size, etc. These genes also affect our abilities and personality. Since Adam embodied two forms of each gene, he, Adam, provided all human genetic diversity. Two forms of each gene coupled with epigenetics would allow Adam’s genome to produce an infinite number of unique humans.

We are Adam

Because we all share Adam’s DNA, the Bible calls us all, collectively, “Adam.” Please read this scripture very carefully; the keywords here are “them” and “their:”

Genesis 5:2  Male and female created he them; and blessed them, and called their name Adam, in the day when they were created. (KJV)

So, God called their name Adam; we are Adam. When Adam sinned, he became corruptible and took on a sinful nature. Since Adam embodied all humanity, we all went down with him and took on his sinful nature. This sin nature causes corruption of our genes in the form of mutations. Today, every generation has approximately 100 more genetic mutations than the previous generation. These mutations can result in deformation, disorders, and disease; genetic mutations are never good, and we rightly call them “mutations.” Our mutation accumulation is discouraging, but we have the promise that in the twinkling of an eye, our DNA will return to its day-6 splendor. This is good news; this is the Gospel.

 Behold, I shew you a mystery; We shall not all sleep, but we shall all be changed,

 In a moment, in the twinkling of an eye, at the last trump: for the trumpet shall sound, and the dead shall be raised incorruptible, and we shall be changed.

For this corruptible must put on incorruption, and this mortal must put on immortality. (KJV  I Corinthians 15:51-53 )

Our Future

My dear friends and children, our future is very bright: We are Adam and have the hope of redemption and obtaining our original, day-six DNA. Our bodies will be perfect. We will be in the Kingdom of God, no longer mortal and no longer sinful.

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Find Your Ancient Biblical Ancestor – Noah’s Sons

With this paper,  you can find your ancient Biblical ancestor. Is it Shem, Ham, or Japheth? At Genesis and Genetics, we have examined Y-chromosome genomes searching for Noah and his three sons. They were easy to find. According to our analysis, if you have the rs17306671 Y-chromosome mutation nucleotide A, you are from Shem. The rs9786139 Y-chromosome mutation nucleotide A means you are from Ham. And if you have the rs3900 Y-chromosome mutation nucleotide G, you are from Japheth. Of course, if you are a woman, you don’t have a Y-chromosome; so, you will have to get your father’s or brother’s DNA.

Background 

Here is some background: Y-chromosome DNA is found only in men. Consequently, men pass it down to their sons and their son’s sons, etc. The Y-chromosome has approximately 60 million base pairs, each subject to mutations. Mutations develop in the Y-chromosome, typically at the rate of 2 mutations per generation (Reference 1 and 30 years per generation). Therefore, these mutations are genetic markers that allow us to track ancestry. Our findings are consistent with the Bible and modern science raw data.

Consequently, if one man populated all the earth, all males would have his Y-chromosome. Then, if this man had two sons, one would expect that roughly half of the world would have one son’s mutations and the other half would have the other son’s mutations. Furthermore, if our original ancestor had ten grandsons, one would expect each grandson to have mutations in approximately 10 percent of the male population. Successive generations would continue to generate new mutations that would form a human family tree. Geneticists call this tree a phylogenetic tree.

Procedure – Y-chromosome Analysis

The following presents the easy-to-follow logic and analysis which anyone can repeat.

We started by looking for all Y-chromosome mutations/markers with a frequency of more than 5 percent. This was easy by taking existing phylogenetic trees and looking for which markers had a frequency of more than 5 % of the population. 

Next, we took one single human Y-chromosome genome (HG02461 a man from Gambia, Africa).  We found that he had a marker at L15, re9786139. This marker is in approximately 38 percent of the world’s male population. So, we knew our African from Gambia came from our ancient ancestor with the L15 marker.  

Then we continued to look at individual human genomes from other places in Africa, Japan, China, Europe, South America, and North America. We found that all our subjects were related to one of just three major groups. Specifically, these groups were L15/ rs9786139, M9/ rs3900, and M429/ rs17306671. The implication is that our original male ancestor had three sons. Consequently, all male humans were born from these three sons.

Data

The data used in this research came from the 1000 genomes project (Reference 2) and was retrieved using the Ensembl browser (Reference 3). The data appeared to be correct with no errors. We eliminated no data due to suspect errors, and no data was “cherry-picked” to suit any preconceived ideas. Our thanks to the great effort of those who did the sequencing and publishing of the raw data. We also greatly appreciate that it was made available to the public.

Spreadsheets – Ancient Ancestors

The spreadsheet below documents 57 Y-genomes of diverse people (Americas, East Asia, Europe, South Asia, and Africa). It provides 57 rows (individual male humans) and 30 columns (mutations over 5 percent of the population). Each column element of the matrix was color-coded to show us whether the individual had the mutation or not. We noticed patterns beginning to form (you can CLICK HERE to see the EXCEL copy.)

 

Find your ancient Biblical ancestor via Y-chromosome (image 1)
Find your ancient Biblical ancestor via Y-chromosome (image 1)

Next, we switched columns and rows to form groups. Then, we arranged the mutations in descending order based on MAF percentage. A clear pattern emerged, as one can see in the figure below. We see that each individual fits into just one group and has no mutations in any other group. Also, we see that every individual in each group has the mutation with the greatest MAF; this is the mutation of the most ancient ancestor of that group. Here is what the spreadsheet looks like after grouping: Note: you can CLICK HERE to see the matrix in EXCEL. This image will allow you to find your ancient Biblical ancestor: Shem, Ham, or Japheth

Find your ancient Biblical ancestor via Y-chromosome (image 2)
Find your ancient Biblical ancestor via Y-chromosome (image 2)

Looking at the matrix above, we see that each group has one maximum MAF. The yellow is .38, the red is .52, and the green is .10. They add up to 100 percent.

Biblical Narrative

Now that we have shown that our most ancient ancestor had three sons, we can state that this finding is consistent with the Bible. The three groups are compatible with the three sons of Noah: Ham, Shem, and Japheth. The Bible states that, generally, those from Ham went south to Africa and southern Asia, those from Japheth went north to northern Europe and northern Asia, and those from Shem stayed in the Caucuses, the Near East, and North Africa. Therefore, one could easily conclude that Ham is the yellow group, Shem is the green group, and Japheth is the red group. Note: We now know Noah’s Y-chromosome since it is the genome of the three sons with all mutations removed.

Bible in Genesis 10, the Table of Nations, states that all humanity came from these three sons:

Genesis 10:1  Now these are the generations of the sons of Noah, Shem, Ham, and Japheth: and unto them were sons born after the flood.

Genesis 10:32  These are the families of the sons of Noah, after their generations, in their nations: and by these were the nations divided in the earth after the flood.

Results

Therefore, we can assume that roughly 1/3 of the earth’s male population came from each son, but, since Japheth had seven sons, Ham had four sons, and Shem had five sons; therefore, the following world percentages are more applicable:

Patriarch   Number of sons    % Projected World Population        Observation

Japheth        7 sons                                              43.75                                        52

Ham                4 sons                                              25                                              38

Shem              5 sons                                              31.25                                        10

The chart above shows that the Ham and Japheth results were higher than expected, and Shem was lower than expected. However, the following explains the differences:

(1) The Ham and Japheth offspring are in the world’s heavily populated areas, namely South and East Asia.

(2) The Thousand Genomes Project did not provide representatives of the Near East, the Mid-East, or Northern Africa, all of which would increase the Shem percentage, thereby decreasing Ham and Japheth’s percentages.

The above two issues are not meant as criticism but offered as an explanation.

Historical Evidence

Our findings are consistent with the Bible, ancient secular history, and genetic diversity:

  1. The Bible documents Noah and his family as the only ones spared from the deluge that flooded the entire earth, and  Noah’s three sons repopulated the world.
  2. The historical period began when the Sumerians began writing cuneiform tablets. These early writings documented the kings before and after the flood. Also, the Sumerian legends are consistent with three sons repopulating the world. These three sons were t
  3. According to the Bible and Sumerian history, all humanity came from one family. As they migrated throughout the world, those separated into satellite groups lost their genetic diversity; therefore, the most genetic diversity should be where Noah’s family settled, the Near East. Those who migrated to the Americas, Australia, and southern Africa lost genetic diversity. We can consider two levels of observing genetic diversity, first, what we see and, second, what DNA tells us. We can easily see eye color, skin color, and hair color. Looking at a globe, it is apparent that those with the most visual diversity meet in the Near East, the place of disembarkation from Noah’s Ark. From a DNA standpoint, one can look at the diversity of haplogroups, both Y-chromosomal and mitochondrial. The extremities are South Africa, Australia, and the Americas, with only a few haplogroups. The location with the most haplogroups is in the Near East.

Summary

(1) Anyone can trace their ancient ancestry back to Shem, Ham, or Japheth by using our method. Women will need DNA from a father, brother, or some other male relative.

(2) From a Y-chromosome perspective, it appears that all humanity came from three male humans.

(3) Item (1) is not proof of the Biblical narrative concerning Noah’s three sons, but it is consistent with it. To prove it, one would have to sequence every human male ever born and analyze his genome.

(4) We can now project Noah’s DNA; it is that of his three sons with no mutations.

(5) Our findings are consistent with the Bible, Sumerian history, and our current state of human diversity.

Future analysis It is now possible to know the Y-chromosome DNA of Noah’s grandchildren. 

References:

1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748900/#:~:text=The%20chromosomes%20were%20separated%20by,7.0%20%C3%97%2010%E2%88%928).

2 https://www.internationalgenome.org/

3 https://useast.ensembl.org/index.html

Appendix A

If you want to repeat this analysis or add to it, you may use our step-by-step procedure.

Let’s start by taking someone from, perhaps, Peru and find out to which group he belongs. Did he come from Shem, Ham, or Japheth?

(1) We open Ensembl (https://useast.ensembl.org/index.html ). Leave everything default and enter rs9786139 in the upper right-hand box—hit enter.

(2) You should get a new window with the following “rs9786139 (Human Variant).” Click on it. Notice that the MAF is .38.

(3) Click on the ICON that says, “population genetics.” Scroll down to find “AMR” and the subgroup “PEL.” Click on the “PEL.” You can see that 95 percent of this group has a “G,” and 5 percent of the population have an “A.” Next, go to the far right of the “PEL” row and click on “show.” Each of the rows of this screen is an actual human being. You will notice that most of this group has a “G,” but a few have an “A.”

(4) Looking at the population genetics of those from PEL, Peru, you can see that a few Peruvians are from Ham, but most are from someone else. You can find out who by entering the defining mutations for Shem and Japheth. If you enter all the mutations and analyze the same Peruvian, you will see all his mutations fall into one group. If you look at rs3900, you will see that most Peruvians are from Japheth.

(5) continue entering the mutations one by one, and you will see that our Peruvian is only from one group and has no mutations from any other group. If you do a significant number of individuals, please send them to us.

In addition:

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